Month: May 2021

Genotyping cancer-associated genes in chordoma identifies mutations in oncogenes and areas of chromosomal loss involving CDKN2A, PTEN, and SMARCB1.

Genotyping cancer-associated genes in chordoma identifies mutations in oncogenes and areas of chromosomal loss involving CDKN2A, PTEN, and SMARCB1.

The molecular mechanisms underlying chordoma pathogenesis are unknown. We due to this fact sought to determine novel mutations to higher perceive chordoma biology and to doubtlessly determine therapeutic targets. Given the comparatively excessive prices of entire genome sequencing, we carried out a centered genetic evaluation utilizing matrix-assisted laser desorption/ionization-time of flight mass spectrometer (Sequenom iPLEX genotyping). We examined 865 hotspot …

Genotyping cancer-associated genes in chordoma identifies mutations in oncogenes and areas of chromosomal loss involving CDKN2A, PTEN, and SMARCB1. Read More »

Novel Multiplex and Loop-Mediated Isothermal Amplification (LAMP) Assays for Rapid Species and Mating-Type Identification of Oculimacula acuformis and O. yallundae (Causal Agents of Cereal Eyespot), and Application for Detection of Ascospore Dispersal and in planta Use

Novel Multiplex and Loop-Mediated Isothermal Amplification (LAMP) Assays for Rapid Species and Mating-Type Identification of Oculimacula acuformis and O. yallundae (Causal Agents of Cereal Eyespot), and Application for Detection of Ascospore Dispersal and in planta Use

Eyespot, attributable to the associated fungal pathogens Oculimacula acuformis (OA) and O. yallundae (OY), is a vital cereal stem-base illness in temperate elements of the world. Both species are dispersed primarily by splash-dispersed conidia however are additionally recognized to bear sexual replica yielding apothecia containing ascospores. Field prognosis of eyespot could be difficult with different …

Novel Multiplex and Loop-Mediated Isothermal Amplification (LAMP) Assays for Rapid Species and Mating-Type Identification of Oculimacula acuformis and O. yallundae (Causal Agents of Cereal Eyespot), and Application for Detection of Ascospore Dispersal and in planta Use Read More »